Single Nuclei Sequencing Reveals Replication Stress in Adrenocortical Carcinoma
Liudmila V. Popova, Elizabeth A. R. Garfinkle, Daniel M. Chopyk, Jaye B. Navarro, Adithe Rivaldi, Yaoling Shu, Elena E. Lomonosova, John E. Phay, Barbra S. Miller, Swati Sattuwar, Mary M. Mullen, Elaine R. Mardis, Katherine E. Miller, Priya H. Dedhia
The paper uses single nuclei RNA sequencing to identify replication stress and DNA damage response in adrenocortical carcinoma, suggesting ATR as a potential therapeutic target.
bioRxiv · Sep 30, 2024 · PreprintCancer Biology