Liudmila V. Popova

This study shows Hat1 regulates H3K9 methylation and HMT localization in LADs, affecting heterochromatin structure and inheritance in mouse cells.

This paper develops patient-derived ACC tumor constructs to evaluate therapeutic strategies, showing they can test chemotherapies, targeted therapies, and immunotherapies.

This study shows MMP-14 is critical for ACC cell survival and DNA repair, and its inhibition reduces viability and impairs repair mechanisms.

The paper identifies three distinct LAD classes based on histone modification patterns in mouse MEF cells, revealing heterochromatin-specific regulatory roles.

The paper uses single nuclei RNA sequencing to identify replication stress and DNA damage response in adrenocortical carcinoma, suggesting ATR as a potential therapeutic target.

This study shows HAT1 acetylates new histones during DNA replication, regulating chromatin state inheritance and nuclear lamina-heterochromatin interactions.