Author

Jean-Philippe Julien

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Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Christine BeariD· 1 shared Christopher E Ing· 1 shared Hong Cui· 1 shared June Ereño-Oreba· 1 shared Maurita Hung· 1 shared Mohabir Ramjeesingh· 1 shared Régis PomèsiD· 1 shared Stephanie Chin· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBiophysics

Christine BearORCID

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1 paper

Recent·Most cited

Lipid interactions enhance activation and potentiation of cystic fibrosis transmembrane conductance regulator (CFTR)

Stephanie Chin, Mohabir Ramjeesingh, Maurita Hung, June Ereño-Oreba, Christopher E Ing, Zhi W. Zeng, Hong Cui, Jean-Philippe Julien, Régis Pomès, Christine Bear

This study shows that lipid interactions are crucial for CFTR channel activation and potentiation, as demonstrated by higher catalytic activity and response to ivacaftor when CFTR is purified with associated lipids.

bioRxiv · Dec 16, 2018 · PreprintBiophysics