Structural Insights into Immature Dengue Virus-Like Particles Revealed by Cryo-EM and Molecular Dynamics Simulations
Palur Venkata Raghuvamsi, Guanwen Chen, Day‐Yu Chao, Ya‐Na Wu, Jedhan Ucat Galula, Chun-Hsiung Wang, Peter John Bond, Jan K. Marzinek, Shang‐Rung Wu
This study presents the cryo-EM structure of immature dengue serotype 2 VLPs and uses MD simulations to reveal their maturation mechanism and lipid dependency.
bioRxiv · Jan 21, 2025 · PreprintBioinformatics