Author

Jeffrey A. Tredup

Bristol-Myers Squibb (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Alaric J. DyckmaniD· 1 shared Asmita Choudhury· 1 shared Cameron M. MessieriD· 1 shared Chunshan Xie· 1 shared David Critton· 1 shared David L Hope· 1 shared Janet Caceres‐CortesiD· 1 shared John A. NewittiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Alaric J. DyckmanORCID

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1 paper

Recent·Most cited

Orthosteric STING inhibition elucidates molecular correction of SAVI STING

Tao Xie, Max Ruzanov, David Critton, Leidy C. Merselis, Joseph G. Naglich, John S. Sack, Ping Zhang, Chunshan Xie, Jeffrey A. Tredup, Laurel B. Stine, Cameron M. Messier, David L Hope, Janet Caceres‐Cortes, Luciano Mueller, Alaric J. Dyckman, , Stephen C. Wilson

This study identifies a critical residue for STING activation and shows how an orthosteric inhibitor can partially correct a SAVI mutation.

Nature Communications · Jul 1, 2025Peer-reviewedMolecular Biology