Ping Zhang

This study corrects a pathogenic ATAD3A variant in iPSCs using CRISPR-Cas9-induced gene conversion without donor templates, showing high efficiency and dependence on HR proteins.

This study identifies a critical residue for STING activation and shows how an orthosteric inhibitor can partially correct a SAVI mutation.

The paper tracks T cell responses over time in the tuberculin skin test to identify Mtb-reactive T cell metaclones that are immunodominant across individuals.

The paper identifies eQTLs and regulatory networks linking genetic variation to transcriptomic responses in sepsis, highlighting key regulators like HIF1A and CEBPB.

The paper identifies heritable genetic variants in cancer genes that associate with both cancer risk and anthropometric traits in a large cohort.