Regulation of trehalose biosynthesis and thermotolerance by the Cryptococcus neoformans HECT E3 ubiquitin ligase Rsp5
Alejandro L. Antonia, Lukas M. du Plooy, Siobhan R. Duffy, Jeffrey F. Kuhn, Erik J. Soderblom, J. Andrew Alspaugh
This study shows that Rsp5 ubiquitination regulates trehalose biosynthesis in C. neoformans, enhancing thermotolerance and salt stress resistance.
bioRxiv · Jan 7, 2026 · PreprintMicrobiology