Cell confinement initiates a delayed but heritable loss of chromosomes
Steven H. Phan, M Y Wang, Kayla R. Snare, Jonah Kandell, Jeneille Deans, Panteleimon Rompolas, Guilherme P. F. Nader, Dennis E. Discher
The paper shows that cell confinement causes delayed, heritable chromosome loss, which is linked to mitotic memory and has implications for cancer evolution.
Cell Reports · Mar 1, 2026Peer-reviewedCell Biology