Author

Jennifer E. Cassels

University of Glasgow

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Alastair SmithiD· 1 shared Alexander Winton· 1 shared Alexandra Curran· 1 shared Alison M. MichieiD· 1 shared Anindita RoyiD· 1 shared Aya Gouma· 1 shared Brenda E. S. Gibson· 1 shared Christine J. HarrisoniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

Alastair SmithORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

CD180 identifies chemoresistant stem-like blasts and reveals a KMT2A-driven vulnerability in acute myeloid leukaemia

Madonna M. Eltoukhy, Alexander Winton, Francesca Fasanella Masci, Elżbieta Kania, Mary T. Scott, Alastair Smith, Evie Rigby, Alexandra Curran, Aya Gouma, Jennifer E. Cassels, Lijun Liu, Thomas Stevens, Karen M. Dunn, Kevin M. Rattigan, Meaad almowaled, , Karen Keeshan

This paper identifies CD180 as a marker for chemoresistant stem-like blasts in KMT2A-rearranged paediatric AML, showing its absence on normal HSCs and its role as a therapeutic target.

bioRxiv · Apr 27, 2026 · PreprintCancer Biology

The chemical chaperone 4-phenylbutyric acid rescues molecular cell defects of COL3A1 mutations that cause vascular Ehlers Danlos Syndrome

Ramla Omar, Michelle Lee, Laura Gonzalez-Trueba, Spyridonas Lianos, Snoopy Hazarika, Malak A Ammar, Jennifer E. Cassels, Alison M. Michie, Neil John Bulleid, Fransiska Malfait, Tom Van Agtmael

This study shows that 4-phenylbutyric acid rescues molecular defects in COL3A1 mutations causing vEDS by reducing ER stress and improving collagen secretion.

bioRxiv · Jun 20, 2024 · PreprintGenetics