Quantitative single cell 5hmC sequencing reveals non-canonical gene regulation by non-CG hydroxymethylation
Emily B. Fabyanic, Peng Hu, Qi Qiu, Kiara N. Berríos, Daniel R. Connolly, Tong Wang, Jennifer Flournoy, Zhaolan Zhou, Rahul M. Kohli, Hao Wu
This study develops snhmC-seq to quantify 5hmC in single cells and identifies non-canonical gene regulation by non-CG 5hmC in mouse brain.
Nature Biotechnology · Aug 28, 2023Peer-reviewedGenomics