Functional diversification of Ser-Arg rich protein kinases to control ubiquitin-dependent neurodevelopmental signalling
Francisco Bustos, Anna Segarra-Fas, Gino Nardocci, Andrew Cassidy, Odetta Antico, Lindsay Davidson, Lennart Brandenburg, Thomas Macartney, Rachel L. Toth, C. James Hastie, Jennifer Moran, Robert Gourlay, Joby Varghese, Renata Filipe Soares, Martin A. Montecino, Greg M. Findlay
The paper shows SRPK regulates ubiquitin-dependent neurodevelopmental signalling by phosphorylating RNF12, linking SRPK mutations to intellectual disability.
Developmental Cell · Oct 19, 2020Peer-reviewedDevelopmental Biology