Developmental BiologybioRxivPreprint
SorCS2 binds progranulin and regulates motor axon outgrowth
Pernille Bogetofte Thomasen, A Salašová, Hande Login…·Anders Nykjær
This study identifies SorCS2 as a receptor for progranulin that regulates motor axon outgrowth in zebrafish and mice, with loss-of-function phenotypes observed in both species.