Integrating Single-Cell Biophysical and Transcriptomic Features to Resolve Functional Heterogeneity in Mantle Cell Lymphoma
Ye Zhang, Lydie L. Debaize, Adam Langenbucher, Jenalyn Weekes, Ioulia Vogiatzi, Teemu P. Miettinen, Mingzeng Zhang, Emily Sumpena, Huiyun Liu, Sarah Marie Duquette, Liam R. Hackett, Jeremy Zhang, Sona Baghiyan, Robert Allyn Redd, Martin J. Aryee, , Mark Alan Murakami
This study integrates single-cell biophysical and transcriptomic data to identify clinically relevant phenotypes in mantle cell lymphoma, linking biophysical properties to gene expression and drug response.
Science Advances · Dec 5, 2025Peer-reviewedCancer Biology