Adam Langenbucher

This study identifies tumor-intrinsic stress states as modulators of CAR T cell therapy response in pancreatic cancer using CRISPR screens and single-cell genomics.

This study integrates single-cell biophysical and transcriptomic data to identify clinically relevant phenotypes in mantle cell lymphoma, linking biophysical properties to gene expression and drug response.

This study shows that APOBEC mutagenesis occurs in both tumor and viral genomes in HPV+ OPSCC, suggesting a direct link between viral restriction and host mutations.