Author

Jessica L. Swanson

University of Minnesota

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Neuroscience· 1

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Filip HanakiD· 1 shared Kenneth E. BernsteiniD· 1 shared Krzysztof FelczakiD· 1 shared Patrick E. RothwelliD· 1 shared Prakashkumar DobariyaiD· 1 shared Swati S. MoreiD· 1 shared Ursula C.H. Girdwood· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Filip HanakORCID

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1 paper

Recent·Most cited

Inhibition of the angiotensin-converting enzyme N-terminal catalytic domain prevents endogenous opioid degradation in brain tissue

Filip Hanak, Jessica L. Swanson, Krzysztof Felczak, Prakashkumar Dobariya, Ursula C.H. Girdwood, Kenneth E. Bernstein, Swati S. More, Patrick E. Rothwell

This study identifies the N-terminal catalytic domain of ACE as the primary site for endogenous opioid peptide degradation in brain tissue and shows that inhibiting this domain reduces opioid degradation.

JCI Insight · Nov 18, 2025Peer-reviewedNeuroscience