Chemical precision glyco-mutagenesis by glycosyltransferase engineering in living cells
Benjamin Schumann, Stacy Alyse Malaker, Simon Wisnovsky, Marjoke F. Debets, Anthony J. Agbay, Daniel Fernández, Lauren J. S. Wagner, Lin Liang, Zhen Li, Junwon Choi, Douglas Fox, Jessie Peh, Melissa Anne Gray, Kayvon Pedram, Jennifer J. Kohler, , Carolyn Ruth Bertozzi
The paper introduces a method to chemically tag glycans in living cells using engineered glycosyltransferases to study glycan structure and biosynthesis.
Molecular Cell · Apr 22, 2020Peer-reviewedSynthetic Biology