Metabolic precision labeling enables selective probing of O-linked N-acetylgalactosamine glycosylation
Marjoke F. Debets, Ömür Y. Tastan, Simon Wisnovsky, Stacy Alyse Malaker, Nikolaos Angelis, Leonhard Möckl, Junwon Choi, Helen R. Flynn, Lauren J. S. Wagner, Ganka Bineva‐Todd, Aristotelis Antonopoulos, Anna Cioce, William M. Browne, Zhen Li, David C. Briggs, , Benjamin Schumann
This paper introduces GalNAzMe, a monosaccharide probe that selectively labels O-GalNAc glycosylation in living cells, enabling detailed study of this cancer-relevant modification.
Proceedings of the National Academy of Sciences · Sep 28, 2020Peer-reviewedSynthetic Biology