Author

Jet S. Bloem

Amsterdam University Medical Centers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Diederik W.D. KusteriD· 1 shared Edgar E. NolletiD· 1 shared Inez DuursmaiD· 1 shared Janaya A. MaloneiD· 1 shared Jolanda van der VeldeniD· 1 shared Kenneth B. MarguliesiD· 1 shared Linda Renata Micali· 1 shared Michelle MichelsiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPhysiology

Diederik W.D. KusterORCID

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Author profile →

1 paper

Recent·Most cited

Microtubule detyrosination alters nuclear mechanotransduction and leads to pro-hypertrophic signaling in hypertrophic cardiomyopathy

Inez Duursma, Linda Renata Micali, Edgar E. Nollet, Valentijn Jansen, Janaya A. Malone, Jet S. Bloem, Kenneth B. Margulies, Stephan A C Schoonvelde, Michelle Michels, Nicole N. van der Wel, Jolanda van der Velden, Tyler J. Kirby, Diederik W.D. Kuster

This study shows that microtubule detyrosination in HCM causes nuclear shape changes and YAP1 signaling, which can be reversed by inhibiting detyrosination.

Journal of Molecular and Cellular Cardiology Plus · Mar 1, 2026Peer-reviewedPhysiology