Jian Young Wu

Venlafaxine stimulates an MMP-9-dependent increase in excitatory/inhibitory balance in a stress model of depression

This study shows venlafaxine increases MMP-9 levels and restores excitatory/inhibitory balance in a stress model of depression.

Venlafaxine stimulates PNN proteolysis and MMP-9 dependent enhancement of gamma power; relevance to antidepressant efficacy

This study shows venlafaxine reduces PNN integrity and increases gamma power via MMP-9 in mice, linking it to antidepressant effects.