Adam Caccavano

This study shows that early-life disruption of the medial pulvinar in marmosets leads to adult prefrontal inhibitory and cognitive deficits relevant to schizophrenia.

This study shows that reducing H3K4 methylation in specific brain regions causes neurodevelopmental disorder-like phenotypes, including seizures, growth issues, and behavioral deficits.

This study investigates how opioid receptors modulate glutamatergic and cholinergic neurotransmission in the medial habenula/interpeduncular nucleus circuit, revealing complex developmental regulation and interactions with potassium channels.

The paper shows that eGlyRs in hippocampal interneurons regulate network activity through developmental and evolutionary conserved mechanisms.

This study shows MMP-2/9 inhibition affects SWR abundance, fear memory, and sociability in juvenile zebrafish, with implications for affective disorders.

The paper identifies enhancer-AAV tools for specific neuronal subtypes and validates them across species.

The paper shows that opioids suppress inhibition in hippocampal PV-INs but not neocortex across species and development, highlighting conserved and divergent roles in neural circuits.

This study shows that sharp wave ripple events occur in zebrafish hippocampal homologue and basolateral amygdala, and are modulated by cholinergic cells.

This study shows that loss of Grin2a causes delayed electrophysiological maturation of hippocampal parvalbumin interneurons, leading to transient seizure susceptibility in mice.

This study shows that parvalbumin basket cells are less active during SWRs in a mouse AD model, contributing to memory impairment.

This study shows venlafaxine reduces PNN integrity and increases gamma power via MMP-9 in mice, linking it to antidepressant effects.

This study evaluates GCaMP-6f's ability to detect subthreshold and fast population neuronal activity, finding it sensitive for low-amplitude events and fast enough for theta oscillations.

This study shows that disrupting perineuronal nets increases sharp wave ripple frequency in the hippocampus of mice.