Katherine E. Conant

This study shows that 4-MU treatment reduces amyloid pathology and improves memory in APP/PS1 mice.

The paper identifies increased HAPLN2 levels in APOE4 mice hippocampus, linking it to extracellular matrix changes and potential Alzheimer's disease risk.

This study investigates how CCL5/CCR5 signaling modulates depression-relevant behaviors, neuronal oscillations, and synaptic plasticity in mice, suggesting potential therapeutic targets for MDD.

This study shows MMP-2/9 inhibition affects SWR abundance, fear memory, and sociability in juvenile zebrafish, with implications for affective disorders.

The paper shows that CCR5 deficiency reduces TIMP levels, improves gamma oscillation power, and enhances learning in APOE4 mice.

This study shows that sharp wave ripple events occur in zebrafish hippocampal homologue and basolateral amygdala, and are modulated by cholinergic cells.

This study shows that parvalbumin basket cells are less active during SWRs in a mouse AD model, contributing to memory impairment.

This study shows venlafaxine increases MMP-9 levels and restores excitatory/inhibitory balance in a stress model of depression.

This study shows venlafaxine reduces PNN integrity and increases gamma power via MMP-9 in mice, linking it to antidepressant effects.

This study shows that disrupting perineuronal nets increases sharp wave ripple frequency in the hippocampus of mice.