ODC1 restricts meningeal B cell age-associated-like phenotype and function in multiple sclerosis: a human and experimental study
Jonathan D. Zurawski, Alara Tuncer, Martin R. Profant, Jianuo Wang, Miranda Green, Yoobhin Park, Ke Cao, Simon Paris, Shahamat Tauhid, Youmna Jalkh, Molly Quattrucci, Renxin Chu, Xingshan Cao, Alex Kiss, Tanuja Chitnis, , Chao Wang
This study shows that ODC1 suppresses age-associated B cell features in meningeal inflammation of MS and EAE, affecting disease severity.
Proceedings of the National Academy of Sciences · Mar 13, 2026Peer-reviewedImmunology