Author

Youmna Jalkh

Brigham and Women's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:imaging· 2 Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1 Research Focus:dimensionality reduction· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Rohit BakshiiD· 2 shared Alara Tuncer· 1 shared Alex KissiD· 1 shared Andrew A. CheniD· 1 shared Anna L. DuValiD· 1 shared Blake E. DeweyiD· 1 shared Chao WangiD· 1 shared Clary B. ClishiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Rohit BakshiORCID

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2 papers

Recent·Most cited

ODC1 restricts meningeal B cell age-associated-like phenotype and function in multiple sclerosis: a human and experimental study

Jonathan D. Zurawski, Alara Tuncer, Martin R. Profant, Jianuo Wang, Miranda Green, Yoobhin Park, Ke Cao, Simon Paris, Shahamat Tauhid, Youmna Jalkh, Molly Quattrucci, Renxin Chu, Xingshan Cao, Alex Kiss, Tanuja Chitnis, , Chao Wang

This study shows that ODC1 suppresses age-associated B cell features in meningeal inflammation of MS and EAE, affecting disease severity.

Proceedings of the National Academy of Sciences · Mar 13, 2026Peer-reviewedImmunology

Deconfounded Dimension Reduction via Partial Embeddings

Andrew A. Chen, Kelly A. Clark, Blake E. Dewey, Anna L. DuVal, Nicole Pellegrini, Govind Nair, Youmna Jalkh, Samar Khalil, Jon Zurawski, Peter A. Calabresi, Daniel S. Reich, Rohit Bakshi, Haochang Shou, Russell Taki Shinohara, the Alzheimer’s Disease Neuroimaging Initiative, the North American Imaging in Multiple Sclerosis Cooperative

The paper introduces the PARE framework to remove confounders from dimension reduction methods, showing it can eliminate batch effects in single-cell data and separate clinical from technical variability in neuroimaging.

bioRxiv · Jan 10, 2023 · PreprintNeuroscience