Endocrine Neural Interactions Regulate Antral CCK2R+ Stem Cells in Gastric Inflammation and Preneoplasia
Biyun Zheng, Hualong Zheng, Ruhong Tu, Fenglin Chen, Jiaoqian Lu, Hiroki Kobayashi, Puran Zhang, Yi Zeng, Guodong Lian, Feijing Wu, Xiaozhong Wang, Xiaofei Zhi, Kexuan Huang, Jin Qian, Quin T. Waterbury, , Timothy Cragin Wang
The paper shows that gastrin loss activates a vagal reflex that promotes CCK2R+ stem cell expansion and preneoplasia in gastric inflammation.
bioRxiv · Aug 31, 2026 · PreprintCell Biology