Single-stranded DNA binding proteins are essential components of the architectural LDB1 protein complex
Xiaokang Wang, Nicholas G. Aboreden, Ying Cai, Jessica C. Lam, Kate A. Henderson, Jiaqi Xiang, Belinda M. Giardine, Ross C. Hardison, Cheryl A. Keller, Lalitha Nagarajan, Stephen J. Brandt, Gerd A. Blobel
This study shows SSBP3 is essential for LDB1-mediated chromatin looping and transcription, and stabilizes LDB1 homodimers.
Molecular Cell · Aug 1, 2025Peer-reviewedGenomics