Author

Jessica C. Lam

Children's Hospital of PhiladelphiaORCID 0000-0001-7409-6701Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genomics· 3 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:spatial domain detection· 2 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Belinda M. GiardineiD· 4 shared Cheryl A. KelleriD· 4 shared Gerd A. BlobeliD· 4 shared Ross C. HardisoniD· 4 shared Haoyue ZhangiD· 2 shared Nicholas G. AboredeniD· 2 shared Susannah C. MidlaiD· 2 shared Xiaokang WangiD· 2 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersGenomics

Belinda M. GiardineORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

GenomicsMolecular CellPeer-reviewedAug 1, 2025

Single-stranded DNA binding proteins are essential components of the architectural LDB1 protein complex

Xiaokang Wang, Nicholas G. Aboreden, Ying Cai…·Gerd A. Blobel

This study shows SSBP3 is essential for LDB1-mediated chromatin looping and transcription, and stabilizes LDB1 homodimers.

4 citations

Molecular BiologyMolecular CellPeer-reviewedDec 24, 2024

LDB1 establishes multi-enhancer networks to regulate gene expression

Nicholas G. Aboreden, Jessica C. Lam, Viraat Y. Goel…·Gerd A. Blobel

This study shows LDB1 directly promotes enhancer-promoter loops and organizes multi-enhancer networks to activate transcription, independent of CTCF, cohesin, or YY1.

61 citationstop 1%

experimental assaygene regulatory network inference

GenomicsbioRxivPreprintNov 9, 2023

Genome folding principles revealed in condensin-depleted mitotic chromosomes

Han Zhao, Yinzhi Lin, En Lin…·Haoyue Zhang

This study investigates genome folding in condensin-depleted mitotic chromosomes, revealing compartmentalization mechanisms distinct from interphase.

2 citations

experimental assay

GenomicsNature CommunicationsPeer-reviewedAug 27, 2021

CTCF and transcription influence chromatin structure re-configuration after mitosis

Haoyue Zhang, Jessica C. Lam, Di Zhang…·Gerd A. Blobel

This study investigates how CTCF and transcription influence chromatin structure reconfiguration after mitosis, revealing their distinct roles in boundary formation and gene domain establishment.

80 citationstop 4%

humanexperimental assay