De novo design of modular and tunable allosteric biosensors
Alfredo Quijano‐Rubio, Andy Hsien-Wei Yeh, Jooyoung Park, Hansol Lee, Robert A. Langan, Scott E. Boyken, Marc J. Lajoie, Longxing Cao, Cameron M. Chow, Marcos C. Miranda, Jimin Wi, Hyo Jeong Hong, Lance J. Stewart, Byung‐Ha Oh, David A. Baker
The paper designs modular biosensors using de novo protein switches that detect various analytes with high sensitivity and modularity.
bioRxiv · Jul 18, 2020 · PreprintSynthetic Biology