Author

Andy Hsien-Wei Yeh

University of WashingtonORCID 0000-0002-9023-776XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:protein design· 2 Assay:protein structure· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Cameron M. ChowiD· 3 shared David A. BakeriD· 3 shared Lance J. StewartiD· 3 shared Alexandra C. WallsiD· 2 shared Alfredo Quijano‐RubioiD· 2 shared David VeesleriD· 2 shared John E. BoweniD· 2 shared Laura A. VanBlarganiD· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersSynthetic Biology

Cameron M. ChowORCID

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3 papers

Recent·Most cited

Molecular BiologyNature BiotechnologyPeer-reviewedApr 28, 2022

Detection of antibodies neutralizing historical and emerging SARS-CoV-2 strains using a thermodynamically coupled de novo biosensor system

Jason Z. Zhang, Andy Hsien-Wei Yeh, Alexandra C. Walls…·David A. Baker

The paper introduces a thermodynamically coupled biosensor to rapidly detect neutralizing antibodies against SARS-CoV-2 strains in serum samples.

36 citations

protein structureexperimental assay

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Synthetic BiologyScience Translational MedicinePeer-reviewedApr 12, 2022

Multivalent designed proteins protect against SARS-CoV-2 variants of concern

Andrew C. Hunt, James Brett Case, Young‐Jun Park…·David A. Baker

The paper designs and characterizes trivalent miniprotein binders that neutralize SARS-CoV-2 variants with low pM IC50 values and provide prophylactic and therapeutic protection in mice.

122 citationstop 1%

humanexperimental assay

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Synthetic BiologybioRxivPreprintJul 18, 2020

De novo design of modular and tunable allosteric biosensors

Alfredo Quijano‐Rubio, Andy Hsien-Wei Yeh, Jooyoung Park…·David A. Baker

The paper designs modular biosensors using de novo protein switches that detect various analytes with high sensitivity and modularity.

9 citations

protein structureexperimental assay

𝕏 PostBluesky