Sex-biased islet β cell dysfunction is caused by the MODY MAFA S64F variant by inducing premature aging and senescence in males
Emily M. Walker, Jeeyeon Cha, Xin Tong, Min Amy Guo, Jin-Hua Liu, Sophia Yu, Donato Iacovazzo, Franck Mauvais‐Jarvis, Sarah Elizabeth Flanagan, Márta Korbonits, John M. Stafford, David Aaron Jacobson, Roland W. Stein
This paper identifies a MAFA S64F variant causing sex-dependent β cell dysfunction and diabetes by accelerating aging and senescence in males.
Cell Reports · Oct 1, 2021Peer-reviewedMolecular Biology