Author

Min Amy Guo

Vanderbilt UniversityORCID 0000-0002-6434-1934Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:protein structure· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Organism:human· 1

Frequent Co-Authors

Emily M. WalkeriD· 2 shared Jeeyeon ChaiD· 2 shared Roland W. SteiniD· 2 shared Xin TongiD· 2 shared David Aaron JacobsoniD· 1 shared Donato IacovazzoiD· 1 shared Franck Mauvais‐JarvisiD· 1 shared Garrett Reynolds· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMolecular Biology

Emily M. WalkerORCID

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2 papers

Recent·Most cited

Defining unique structural features in the MAFA and MAFB transcription factors that control Insulin gene activity

Jeeyeon Cha, Xin Tong, Katie Colbert Coate, Min Amy Guo, Jinhua Liu, Garrett Reynolds, Emily M. Walker, Richard A. Stein, Hassane S. Mchaourab, Roland W. Stein

The paper identifies structural features in MAFA and MAFB transcription factors that influence their DNA-binding and Insulin enhancer activity through structural and functional analysis.

Journal of Biological Chemistry · Oct 30, 2024Peer-reviewedMolecular Biology

Sex-biased islet β cell dysfunction is caused by the MODY MAFA S64F variant by inducing premature aging and senescence in males

Emily M. Walker, Jeeyeon Cha, Xin Tong, Min Amy Guo, Jin-Hua Liu, Sophia Yu, Donato Iacovazzo, Franck Mauvais‐Jarvis, Sarah Elizabeth Flanagan, Márta Korbonits, John M. Stafford, David Aaron Jacobson, Roland W. Stein

This paper identifies a MAFA S64F variant causing sex-dependent β cell dysfunction and diabetes by accelerating aging and senescence in males.

Cell Reports · Oct 1, 2021Peer-reviewedMolecular Biology