Piezo1 and Piezo2 channels in retinal ganglion cells and the impact of Piezo1 stimulation on light-dependent neural activity
Puttipong Sripinun, Lily Pachanin See, Sergei S. Nikonov, Venkata Ramana Murthy Chavali, Vrathasha Vrathasha, Jie He, Joan M. O’Brien, Jingsheng Xia, Wennan Lu, Claire H. Mitchell
This paper shows that Piezo1 and Piezo2 channels are expressed in retinal ganglion cells and that their activation increases light-dependent neural activity and excitability, potentially linking to glaucoma progression.
bioRxiv · Jun 25, 2024 · PreprintNeuroscience