Author

Vrathasha Vrathasha

University of PennsylvaniaORCID 0000-0002-2629-8349Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:ATAC-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Jie HeiD· 3 shared Joan M. O’BrieniD· 3 shared Sergei S. NikonoviD· 3 shared Venkata Ramana Murthy ChavaliiD· 3 shared Ahmara G. RossiD· 1 shared Amy-Ann Edziah· 1 shared Andrew D. WellsiD· 1 shared Anne Marie Berry· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersNeuroscience

Jie HeORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintSep 14, 2026

Variant-to-gene mapping in ocular cell types identifies candidate effector genes for primary open-angle glaucoma

Vrathasha Vrathasha, Matthew C. Pahl, James A. Pippin…·Joan M. O’Brien

This study maps POAG risk variants to candidate effector genes in ocular cell types, identifying ARHGEF12 as a potential target.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintJun 25, 2024

Piezo1 and Piezo2 channels in retinal ganglion cells and the impact of Piezo1 stimulation on light-dependent neural activity

Puttipong Sripinun, Lily Pachanin See, Sergei S. Nikonov…·Claire H. Mitchell

This paper shows that Piezo1 and Piezo2 channels are expressed in retinal ganglion cells and that their activation increases light-dependent neural activity and excitability, potentially linking to glaucoma progression.

5 citations

𝕏 PostBluesky

NeuroscienceScientific ReportsPeer-reviewedJul 16, 2020

Dual SMAD inhibition and Wnt inhibition enhances the differentiation of induced pluripotent stem cells into Retinal Ganglion cells (iPSC-RGCs)

Venkata Ramana Murthy Chavali, Naqi Haider, Sonika Rathi…·Jason A. Mills

This study develops a reproducible method to differentiate iPSCs into RGCs with high purity using dual SMAD and Wnt pathway inhibition.

46 citations

humanbulk RNA-seq

𝕏 PostBluesky