Single-molecule, full-length transcript isoform sequencing reveals disease mutation-associated RNA isoforms in cardiomyocytes
Chenchen Zhu, Jingyan Wu, Han Sun, Francesca Briganti, Benjamin Meder, Wei Wu, Lars Michael Steinmetz
The paper develops a pipeline to identify and quantify full-length RNA isoforms, revealing disease-associated isoforms in cardiomyocytes with RBM20 mutations.
Nature Communications · Jul 9, 2021Peer-reviewedGenetics