Author

Petra Jakob

European Molecular Biology Laboratory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genetics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:human· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Han SuniD· 2 shared Lars Michael SteinmetziD· 2 shared William F. MuelleriD· 2 shared Alejandro Reyes· 1 shared Benedikt RauscheriD· 1 shared Bettina HaaseiD· 1 shared Carolin Blume· 1 shared Chenchen ZhuiD· 1 shared

Activity by Year

2014-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersSystems Biology

Han SunORCID

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Author profile →

3 papers

Recent·Most cited

Patient-derived gene and protein expression signatures of NGLY1 deficiency

Benedikt Rauscher, William F. Mueller, Sandra Clauder‐Münster, Petra Jakob, Mohammad Saiful Islam, Han Sun, Sonja Ghidelli, Markus Böesche, Marcus Bantscheff, Hannah Pflaumer, Paul G. Collier, Bettina Haase, Songjie Chen, Rene Hoffman, Guangwen Wang, , Lars Michael Steinmetz

The paper characterizes gene and protein expression changes in NGLY1 deficiency using patient-derived cells and provides a web resource for the data.

The Journal of Biochemistry · Dec 6, 2021Peer-reviewedSystems Biology

Transcript fusion between CDKN1A and RAB44 caused by exon skipping like mechanism due to disruption of a splice site

Han Sun, Michelle Nguyen, William F. Mueller, Zhuanfen Cheng, Hong Zeng, Chenchen Zhu, Jingyan Wu, Kevin R. Roy, Petra Jakob, Raeka S. Aiyar, Wu Wei, Lars Michael Steinmetz

The paper identifies a recurrent tumor-specific transcript fusion between CDKN1A and RAB44 caused by splice-site mutations and shows its correlation with TP53 inactivation and CDK activation.

bioRxiv · Feb 22, 2019 · PreprintGenetics

Mutated SF3B1 is associated with transcript isoform changes of the genes UQCC and RPL31 both in CLLs and uveal melanomas

Alejandro Reyes, Carolin Blume, Vincent Pelechano, Petra Jakob, Lars M. Steinmetz, Thorsten Zenz, Wolfgang Huber

The paper identifies transcript isoform changes in UQCC and RPL31 associated with SF3B1 mutations in CLL and uveal melanoma, suggesting common molecular effects across cancer types.

bioRxiv · Jul 13, 2014 · PreprintCancer Biology