Maternal mRNA deadenylation is defective in in vitro matured mouse and human oocytes
Yusheng Liu, Wenrong Tao, Shuang Wu, Yiwei Zhang, Hu Nie, Zhenzhen Hou, Jingye Zhang, Zhen Yang, Zi‐Jiang Chen, Jiaqiang Wang, Falong Lu, Keliang Wu
This study identifies impaired maternal mRNA deadenylation as a molecular defect in in vitro matured mouse and human oocytes, leading to abnormal gene expression.
Nature Communications · Jul 2, 2024Peer-reviewedDevelopmental Biology