Sequential and coordinated control of human plasma cell differentiation by IRF4 and BLIMP1 associated with a discriminating ISRE/EICE motif lexicon
Louis Lau, Sneha Lal, Jingyu Fan, Nicholas A. Pease, Harinder Singh
This study identifies an ISRE/EICE motif lexicon that distinguishes IRF4 and BLIMP1 binding during plasma cell differentiation, revealing a temporally ordered regulatory mechanism.
bioRxiv · Oct 5, 2026 · PreprintImmunology