Author

Jirui Chen

Fudan University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Chang-Run GuoiD· 1 shared Dong-Ping Wang· 1 shared Hexin Xu· 1 shared Jinru ZhangiD· 1 shared Motoyuki HattoriiD· 1 shared Shen Cheng· 1 shared Teng XuiD· 1 shared Xin ZhangiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

Chang-Run GuoORCID

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1 paper

Recent·Most cited

Cryo-EM reveals the structural basis of subtype-specific, noncompetitive inhibition of the human P2X3 receptor

Zhixuan Zhao, Dong-Ping Wang, Xin Zhang, Yuan Gao, Hexin Xu, Teng Xu, Shen Cheng, Jirui Chen, Jinru Zhang, Ye Yu, Chang-Run Guo, Motoyuki Hattori

The paper reports the cryo-EM structure of the human P2X3 receptor complexed with sivopixant, revealing subtype-specific allosteric inhibition mechanisms and structural basis for improved selectivity.

bioRxiv · Jan 3, 2026 · PreprintBiophysics