Visualizing the transcription and replication of influenza A viral RNAs in cells by multiple direct RNA padlock probing and in-situ sequencing (mudRapp-seq)
Shazeb Ahmad, Jianhui Li, Joél Schaust, Anne-Sophie Gribling-Burrer, Nina Geiger, Sabine Fischer, Uddhav B. Ambi, Simone Backes, Markus Johannes Ankenbrand, Redmond P. Smyth
This study introduces mudRapp-seq to visualize influenza A viral RNA transcription and replication at the single-cell level, revealing early mRNA expression and differential segment expression.
Nucleic Acids Research · May 23, 2025Peer-reviewedMicrobiology