Functional unknomics: closing the knowledge gap to accelerate biomedical research
Joao Rocha, Satish Arcot Jayaram, Tim J. Stevens, Nadine Muschalik, Rajen D. Shah, Sahar Emran, Cristina Robles, Matthew Freeman, Sean Munro
The paper develops an 'Unknome database' to prioritize understudied proteins and validates their functions using Drosophila RNAi and CRISPR/Cas9.
bioRxiv · Jun 28, 2022 · PreprintMolecular Biology