A Digital Microfluidic Platform for the Microscale Production of Functional Immune Cell Therapies
Samuel R. Little, Niloufar Rahbari, Mehri Hajiaghayi, Fatemeh Gholizadeh, Fanny-Meï Cloarec-Ung, Joel Philips, Hugo Sinha, Alison Hirukawa, David J. H. F. Knapp, Peter John Darlington, Steve C. C. Shih
This paper compares a digital microfluidic electroporation system (triDrop) with commercial systems for engineering human T cells, showing improved viability, efficiency, and reduced dysregulation of pathways.
Analytical Chemistry · May 20, 2025Peer-reviewedBioengineering