Author

John Gitau

Université du Québec à Montréal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Genetic & Genomic Medicine· 1 Plant Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Assay:bulk RNA-seq· 4 Research Focus:differential expression· 4 Organism:human· 3 Research Focus:gene regulatory network inference· 2 Assay:whole-exome sequencing· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Francis MakokhaiD· 3 shared Kennedy Wanjau MwangiiD· 3 shared Godfrey Wagutu· 2 shared Shahin SayediD· 2 shared Alexandra R. HarrisiD· 1 shared Annet KiraboiD· 1 shared Aurore Johary· 1 shared Edwin Kimathi MurungiiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCancer Biology

Francis MakokhaORCID

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Author profile →

5 papers

Recent·Most cited

Drought reshapes enhancer-like nascent transcription and gene regulation in Oryza sativa

Fabian Ortner-Krause, Marina Goliasse, John Gitau, Aurore Johary, Farzaneh Rahmdani, Zoé Joly‐Lopez

This study identifies drought-responsive enhancer-like nascent transcription in rice using PRO-seq and dREG, revealing 2,428 prioritized cis-regulatory elements.

bioRxiv · Jul 14, 2026 · PreprintPlant Biology

Mutational and Expression Profile of ZNF217, ZNF750, ZNF703 Zinc Finger Genes in Kenyan Women Diagnosed with Breast Cancer

Michael Kitoi, John Gitau, Godfrey Wagutu, Kennedy Wanjau Mwangi, Florence Ng’ong’a, Francis Makokha

This study analyzes mutational and expression patterns of ZNF217, ZNF703, and ZNF750 in Kenyan breast cancer patients, finding distinct mutation burdens and expression upregulation in tumors.

bioRxiv · Jul 17, 2025 · PreprintCancer Biology

Whole exome-seq and RNA-seq data reveal unique neoantigen profiles in Kenyan breast cancer patients

Godfrey Wagutu, John Gitau, Kennedy Wanjau Mwangi, Mary Murithi, Elias Melly, Alexandra R. Harris, Shahin Sayed, Stefan Ambs, Francis Makokha

The paper identifies unique neoantigen profiles in Kenyan breast cancer patients using whole exome and RNA sequencing data, highlighting patient-specific mutations and HLA associations.

Frontiers in Oncology · Dec 11, 2024Peer-reviewedGenetic & Genomic Medicine

The Association between the JAK-STAT Pathway and Hypertension among Kenyan Women Diagnosed with Breast Cancer

John Gitau, Godfrey Kinyori, Shahin Sayed, Mohammad Saleem, Francis Makokha, Annet Kirabo

This study investigates the association between JAK-STAT pathway gene expression and hypertension in Kenyan women with breast cancer, finding significant correlations between specific genes and blood pressure metrics.

bioRxiv · Jun 7, 2024 · PreprintCancer Biology

Inference of Rift Valley Fever pathogenesis in Bos taurus using a gene co-expression network

John Gitau, Rosaline Wanjiru Macharia, Kennedy Wanjau Mwangi, Nehemiah Ongeso, Edwin Kimathi Murungi

This study constructs a gene co-expression network to identify genes and regulatory motifs involved in Rift Valley Fever pathogenesis in cattle.

bioRxiv · Nov 28, 2021 · PreprintSystems Biology