Francis Makokha

This study analyzes mutational and expression patterns of ZNF217, ZNF703, and ZNF750 in Kenyan breast cancer patients, finding distinct mutation burdens and expression upregulation in tumors.

This paper introduces LogiCAR designer, a computational method using single-cell transcriptomics to identify logic-gated antigen combinations for CAR therapy, showing improved efficacy and safety compared to existing approaches.

The paper identifies unique neoantigen profiles in Kenyan breast cancer patients using whole exome and RNA sequencing data, highlighting patient-specific mutations and HLA associations.

This study investigates the association between JAK-STAT pathway gene expression and hypertension in Kenyan women with breast cancer, finding significant correlations between specific genes and blood pressure metrics.