Edwin Kimathi Murungi

Natural product-based putative efflux inhibitors restore bedaquiline susceptibility in a drug-resistant Mycobacterium tuberculosis mutant

This study identifies natural product-derived efflux inhibitors that restore bedaquiline susceptibility in drug-resistant Mycobacterium tuberculosis mutants.

Computational Prediction of Plasmodium falciparum Antigen-T-cell Receptor Interactions via Molecular Docking: Implications for Malaria Vaccine Design

This study uses molecular docking to predict Plasmodium falciparum antigen-T-cell receptor interactions, identifying three antigens as potential vaccine candidates.

Identification of mycobacterial efflux pump inhibiting compounds from Berberis holstii Engl. and determination of their mechanism of action

This study identifies compounds from Berberis holstii that inhibit Mycobacterium tuberculosis efflux pumps, showing synergistic effects with spectinomycin.

Design of a multi-epitope camel mastitis vaccine candidate using a reverse vaccinology approach

The paper designs a multi-epitope vaccine candidate for camel mastitis using reverse vaccinology, identifying antigenic and epitopic proteins from bacterial genomes.

Chromosome-scale assembly of the African yam bean genome

The paper reports the chromosome-scale genome assembly of African yam bean using long and short read sequencing combined with Hi-C scaffolding, and annotates 31,614 protein-coding genes.

Inference of Rift Valley Fever pathogenesis in Bos taurus using a gene co-expression network

This study constructs a gene co-expression network to identify genes and regulatory motifs involved in Rift Valley Fever pathogenesis in cattle.

Tsetse blood-meal sources, endosymbionts, and trypanosome infections provide insight into African trypanosomiasis transmission in the Maasai Mara National Reserve, a wildlife-human-livestock interface

The paper identifies tsetse fly blood-meal sources, endosymbiont infections, and trypanosome infections in the Maasai Mara National Reserve, finding that hippopotamus and buffalo are significant hosts and that Sodalis glossinidius endosymbionts correlate with higher trypanosome infection rates.