Author

John R. Klem

University of Louisville

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:zebrafish· 2 Organism:human· 1 Organism:non-human primate· 1

Frequent Co-Authors

C. Ben LovelyiD· 2 shared Aaron Scoresby· 1 shared Alexa BurgeriD· 1 shared Anastasia FelkeriD· 1 shared Ann‐Christin Puller· 1 shared Brooke F. MurrayiD· 1 shared Cassie L. KemmleriD· 1 shared Charles BetziD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersDevelopmental Biology

C. Ben LovelyORCID

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2 papers

Recent·Most cited

Mutation in the Bone Morphogenetic Protein signaling pathway sensitize zebrafish and humans to ethanol-induced jaw malformations

John R. Klem, Tae-Hwi Linus Schwantes-An, Marco Abreu, Michael Suttie, Raèden Gray, Hieu D. L. Vo, Grace Conley, Tatiana Foroud, Leah Flury Wetherill, CIFASD, C. Ben Lovely

The paper identifies Bmp signaling pathway mutations as ethanol-sensitive contributors to jaw malformations in zebrafish and humans.

Disease Models & Mechanisms · Mar 11, 2025Peer-reviewedDevelopmental Biology

Next-generation plasmids for transgenesis in zebrafish and beyond

Cassie L. Kemmler, Hannah R. Moran, Brooke F. Murray, Aaron Scoresby, John R. Klem, Rachel L. Eckert, Elizabeth Lepovsky, Sylvain Bertho, Susan Nieuwenhuize, Sibylle Burger, Gianluca D‘Agati, Charles Betz, Ann‐Christin Puller, Anastasia Felker, Karolína Ditrychová, , Christian Mosimann

The paper introduces next-generation transgenesis tools for zebrafish and other species, including vectors with fluorescent markers and promoters for specific tissue expression.

bioRxiv · Dec 13, 2022 · PreprintGenetics