Hannah R. Moran

This study identifies the pericardium's origin from anterior mesothelial progenitors in zebrafish, distinct from the heart field, and links pericardial stiffness to pediatric cardiomyopathies.

This paper develops zebrafish hand2 Cre and CreERT2 drivers using CRISPR-Cas9 to label mesodermal and ectodermal lineages, revealing lineage contributions to various tissues and vasculature.

The paper identifies conserved notochord-specific enhancers of Brachyury/T/TBXT in vertebrates and shows their role in notochord expression and development.

The paper introduces next-generation transgenesis tools for zebrafish and other species, including vectors with fluorescent markers and promoters for specific tissue expression.

The paper compares zebrafish Switch reporter transgenes to identify those with optimal recombination efficiency and expression patterns for lineage labeling.

The paper investigates the contribution of first and second heart field lineages to the adult zebrafish ventricle, finding persistent cell-based compartmentalization without physical boundaries.