Mycobacterium ulcerans low infectious dose and atypical mechanical transmission support insect bites and puncturing injuries in the spread of Buruli ulcer.
John R. Wallace, Kirstie M. Mangas, Jessica L. Porter, Renee Marcsisin, Sacha J. Pidot, Brian Howden, Till F. Omansen, Weiguang Zeng, Jason K. Axford, Paul D. R. Johnson, Timothy P. Stinear
The paper demonstrates that a low dose of Mycobacterium ulcerans can cause Buruli ulcer through skin punctures from mosquito bites or needles in mice.
bioRxiv · Aug 27, 2016 · PreprintMicrobiology