Sacha J. Pidot

This paper shows that phosphorylation by PknB at T101 promotes WalR dimer formation and strengthens DNA binding, revealing a direct functional link between PknB and WalR.

This study characterizes microbial communities in southeastern Australian montane fens, revealing high diversity and unique taxa not found in other environments.

The paper isolates soil bacteria using diffusion chambers, screens for antibiotic activity, and combines mass spectrometry and genomics to identify known and novel antibiotics from Australian soil samples.

This study identifies cyclic lipodepsipeptides as the molecular basis of haemolytic activity in Chromobacterium haemolyticum and shows their role in biofilm formation and swarming.

This paper describes the discovery of a marine sponge-associated mycobacterium closely related to M. tuberculosis, which shares virulence factors but lacks virulence in mice.

This paper identifies M. ulcerans JKD8049 as a suitable human challenge strain for Buruli ulcer research due to its stability, antibiotic susceptibility, and ability to produce mycolactone.

This study identifies mutations in Mycobacterium tuberculosis that confer resistance to nitroimidazole antibiotics, highlighting the need for monitoring these mutations to manage antibiotic use.

RM-seq detects and quantifies antibiotic resistance mutations in bacterial populations with high sensitivity and accuracy.

The paper demonstrates that a low dose of Mycobacterium ulcerans can cause Buruli ulcer through skin punctures from mosquito bites or needles in mice.