Author

John Santoyo

The University of Texas Southwestern Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Aijie LiuiD· 1 shared Alexyss Johnson· 1 shared Amy Bronikowski· 1 shared Andrew Dang· 1 shared Andrew Sakla· 1 shared Andrew Wadley· 1 shared Arnaldo A. Arbini· 1 shared Baifang Qin· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenetics

Aijie LiuORCID

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2 papers

Recent·Most cited

Candidate Explorer: a tool for discovery, evaluation, and display of mutations causing significant immune phenotypes

Darui Xu, Stephen Lyon, Chun Hui Bu, Sara Hildebrand, Jin Huk Choi, Xue Yun Zhong, Aijie Liu, Emre E. Turer, Zhao Zhang, Evan Nair‐Gill, Hexin Shi, Ying Wang, Duanwu Zhang, Tao Yue, Jeffrey A. SoRelle, , Bruce Beutler

Candidate Explorer identifies causative mutations for immune phenotypes by integrating multiple data features into a score, improving mutation-phenotype association verification in mice.

bioRxiv · Nov 7, 2020 · PreprintGenetics

IFN-γ induces epithelial-to-mesenchymal transition of cancer cells via an unique microRNA processing

U-Ging Lo, Rey-Chen Pong, Diane Yang, Leah Gandee, Elizabeth Hernandez, Andrew Dang, Chung-Jung Lin, John Santoyo, Shi-Hong Ma, Rajni Sonavane, Jun Huang, Shu-Fen Tseng, Loredana Moro, Arnaldo A. Arbini, Payal Kapur, , Jer-Tsong Hsieh

This study shows IFN-γ induces EMT in cancer cells by promoting IFIT5-mediated degradation of suppressive miRNAs, enhancing invasiveness and metastasis.

bioRxiv · Jun 25, 2018 · PreprintCancer Biology