Emre E. Turer

This study shows that type I interferon signaling promotes mucosal inflammation in colitis models, with IFNAR1 inhibition protecting against experimental colitis.

This study identifies the Rab32-LRMDA-Retriever complex as essential for endolysosomal trafficking in innate immune cells, maintaining intestinal immune homeostasis.

This study determines the structure of the Retriever-SNX17 complex using cryo-EM, revealing how SNX17 interacts with Retriever to facilitate endosomal sorting of cargo proteins.

Candidate Explorer identifies causative mutations for immune phenotypes by integrating multiple data features into a score, improving mutation-phenotype association verification in mice.