Author

John White

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:non-human primate· 1

Frequent Co-Authors

Camilo Ayala BretoniD· 1 shared James M. WilsoniD· 1 shared Jason LamontagneiD· 1 shared Jenny A. Greig· 1 shared Jessica A. ChichesteriD· 1 shared Jingxu Zhu· 1 shared Kelly M. Martins· 1 shared Lili WangiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Camilo Ayala BretonORCID

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1 paper

Recent·Most cited

Loss of transgene expression limits liver gene therapy in primates

Jenny A. Greig, Kelly M. Martins, Camilo Ayala Breton, Jason Lamontagne, Yanqing Zhu, Zhenning He, John White, Jingxu Zhu, Jessica A. Chichester, Qi Zheng, Zhe Zhang, Peter L. Bell, Lili Wang, James M. Wilson

This study shows that transgene expression in primate liver declines rapidly after initial transduction, even though vector DNA remains in the nucleus, suggesting that genomic integration may be needed for durable expression.

Nature Biotechnology · Nov 6, 2023Peer-reviewedMolecular Biology